Nuclear shuttling of Y Box binding protein-1, its clinical relevance in cancer and as a therapeutic target

• Auteurs principaux: Vinoth Prasanna Gunasekaran (Auteur), Kumari Nishi (Auteur), Vilwanathan Ravikumar (Auteur), Ganeshan Mathan (Auteur)
• Format: Livre
• Publié: Bangladesh Pharmacological Society, 2016-04-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Y-box binding protein 1 (YB-1) is an imperative biomarker for the clinical out-come of cancer patients. An overexpression of YB-1 in cancerous and adjoining tissues is an indication of aggressiveness and advanced stages. In normal resting cells, YB-1 is localized in cytoplasm while in stress conditi...