Synthesis and cytotoxic evaluation of some novel diarylamide possessing quinoxalinedione based on sorafenib
A series of novel sorafenib analogues containing a quinoxalinedione ring and amide linker were synthesized. A total of 9 novel compounds in 6 synthetic steps were synthesized. Briefly, the amino group of p-aminophenol was first protected which then followed by O-arylation with 5-chloro-2-nitroanilin...
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| Formáid: | LEABHAR |
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Wolters Kluwer Medknow Publications,
2018-01-01T00:00:00Z.
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A1234.567 |
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