Molecular regulation of urea cycle function by the liver glucocorticoid receptor

• Главные авторы: Jürgen G. Okun (Автор), Sean Conway (Автор), Kathrin V. Schmidt (Автор), Jonas Schumacher (Автор), Xiaoyue Wang (Автор), Roldan de Guia (Автор), Annika Zota (Автор), Johanna Klement (Автор), Oksana Seibert (Автор), Achim Peters (Автор), Adriano Maida (Автор), Stephan Herzig (Автор), Adam J. Rose (Автор)
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• Опубликовано: Elsevier, 2015-10-01T00:00:00Z.
• Предметы: article
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Objective: One of the major side effects of glucocorticoid (GC) treatment is lean tissue wasting, indicating a prominent role in systemic amino acid metabolism. In order to uncover a novel aspect of GCs and their intracellular-receptor, the glucocorticoid receptor (GR), on metabolic control, we cond...