Molecular regulation of urea cycle function by the liver glucocorticoid receptor

• Main Authors: Jürgen G. Okun (Author), Sean Conway (Author), Kathrin V. Schmidt (Author), Jonas Schumacher (Author), Xiaoyue Wang (Author), Roldan de Guia (Author), Annika Zota (Author), Johanna Klement (Author), Oksana Seibert (Author), Achim Peters (Author), Adriano Maida (Author), Stephan Herzig (Author), Adam J. Rose (Author)
• Format: Book
• Published: Elsevier, 2015-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: One of the major side effects of glucocorticoid (GC) treatment is lean tissue wasting, indicating a prominent role in systemic amino acid metabolism. In order to uncover a novel aspect of GCs and their intracellular-receptor, the glucocorticoid receptor (GR), on metabolic control, we cond...