Determining seropositivity-A review of approaches to define population seroprevalence when using multiplex bead assays to assess burden of tropical diseases.

• Main Authors: YuYen Chan (Author), Kimberly Fornace (Author), Lindsey Wu (Author), Benjamin F Arnold (Author), Jeffrey W Priest (Author), Diana L Martin (Author), Michelle A Chang (Author), Jackie Cook (Author), Gillian Stresman (Author), Chris Drakeley (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Serological surveys with multiplex bead assays can be used to assess seroprevalence to multiple pathogens simultaneously. However, multiple methods have been used to generate cut-off values for seropositivity and these may lead to inconsistent interpretation of results...