Modified Pulsatillae decoction inhibits DSS-induced ulcerative colitis in vitro and in vivo via IL-6/STAT3 pathway

• Main Authors: Shaohua Huangfu (Author), Renjie Dou (Author), Sixia Zhong (Author), Mengjie Guo (Author), Chunyan Gu (Author), Artur Jurczyszyn (Author), Ye Yang (Author), Bin Jiang (Author)
• Format: Book
• Published: BMC, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Ulcerative colitis (UC) is a chronic inflammatory disorder of the colon and rectum, which is positively correlated with the occurrence of IBD-related colorectal cancer (IBD-CRC). Conventional therapies based on drugs such as corticosteroids, mesalamine, and immunosuppression have...