Evaluation of Immunohistochemical Markers, CK17 and SOX2, as Adjuncts to p53 for the Diagnosis of Differentiated Vulvar Intraepithelial Neoplasia (dVIN)

• Main Authors: Shatavisha Dasgupta (Author), Senada Koljenović (Author), Thierry P. P. van den Bosch (Author), Sigrid M. A. Swagemakers (Author), Nick M. A. van der Hoeven (Author), Ronald van Marion (Author), Peter J. van der Spek (Author), Helena C. van Doorn (Author), Folkert J. van Kemenade (Author), Patricia C. Ewing-Graham (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Histological diagnosis of differentiated vulvar intraepithelial neoplasia (dVIN), the precursor of human papillomavirus (HPV)-independent vulvar squamous cell carcinoma (VSCC), can be challenging, as features of dVIN may mimic those of non-dysplastic dermatoses. To aid the diagnosis, p53-immunohisto...