Inactivation of Minar2 in mice hyperactivates mTOR signaling and results in obesity

• Main Authors: Saran Lotfollahzadeh (Author), Chaoshuang Xia (Author), Razie Amraei (Author), Ning Hua (Author), Konstantin V. Kandror (Author), Stephen R. Farmer (Author), Wenyi Wei (Author), Catherine E. Costello (Author), Vipul Chitalia (Author), Nader Rahimi (Author)
• Formato: Libro
• Publicado: Elsevier, 2023-07-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Objective: Obesity is a complex disorder and is linked to chronic diseases such as type 2 diabetes. Major intrinsically disordered NOTCH2-associated receptor2 (MINAR2) is an understudied protein with an unknown role in obesity and metabolism. The purpose of this study was to determine the impact of...