TDP-43 mislocalization drives neurofilament changes in a novel model of TDP-43 proteinopathy
Mislocalization of the TAR DNA-binding protein 43 (TDP-43; encoded by TARDBP) from the nucleus to the cytoplasm is a common feature of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). The downstream in vivo cellular effects of thi...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
The Company of Biologists,
2021-02-01T00:00:00Z.
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