Automated high-content assay for compounds selectively toxic to Trypanosoma cruzi in a myoblastic cell line.

• Main Authors: Julio Alonso-Padilla (Author), Ignacio Cotillo (Author), Jesús L Presa (Author), Juan Cantizani (Author), Imanol Peña (Author), Ana I Bardera (Author), Jose J Martín (Author), Ana Rodriguez (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, represents a very important public health problem in Latin America where it is endemic. Although mostly asymptomatic at its initial stage, after the disease becomes chronic, about a third of the infected patients progress...