Monoclonal antibodies against peptidorhamnomannans of Scedosporium apiospermum enhance the pathogenicity of the fungus.

• Main Authors: Livia C L Lopes (Author), Rodrigo Rollin-Pinheiro (Author), Allan J Guimarães (Author), Vera C B Bittencourt (Author), Luis R Martinez (Author), Wade Koba (Author), Sandra E Farias (Author), Joshua D Nosanchuk (Author), Eliana Barreto-Bergter (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Scedosporium apiospermum is part of the Pseudallescheria-Scedosporium complex. Peptidorhamnomannans (PRMs) are cell wall glycopeptides present in some fungi, and their structures have been characterized in S. apiospermum, S. prolificans and Sporothrix schenckii. Prior work shows that PRMs can intera...