PXR and CAR single nucleotide polymorphisms influence plasma efavirenz levels in South African HIV/AIDS patients

• Main Authors: Swart Marelize (Author), Whitehorn Heather (Author), Ren Yuan (Author), Smith Peter (Author), Ramesar Rajkumar S (Author), Dandara Collet (Author)
• Format: Book
• Published: BMC, 2012-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>This study investigated variation in <it>NR1I2</it> and <it>NR1I3</it> and its effect on plasma efavirenz levels in HIV/AIDS patients. Variability in plasma drug levels has largely led research on identifying...