β-cyclodextrin chitosan-based hydrogels with tunable pH-responsive properties for controlled release of acyclovir: design, characterization, safety, and pharmacokinetic evaluation

• Hlavní autoři: Nadia Shamshad Malik (Autor), Mahmood Ahmad (Autor), Mohammed S. Alqahtani (Autor), Arshad Mahmood (Autor), Kashif Barkat (Autor), Muhammad Tariq Khan (Autor), Ume Ruqia Tulain (Autor), Ayesha Rashid (Autor)
• Médium: Kniha
• Vydáno: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

In this work, series of pH-responsive hydrogels (FMA1-FMA9) were synthesized, characterized, and evaluated as potential carrier for oral delivery of an antiviral drug, acyclovir (ACV). Different proportions of β-cyclodextrin (β-CD), chitosan (CS), methacrylic acid (MAA) and N' N'-methylene...