β-cyclodextrin chitosan-based hydrogels with tunable pH-responsive properties for controlled release of acyclovir: design, characterization, safety, and pharmacokinetic evaluation

• Main Authors: Nadia Shamshad Malik (Author), Mahmood Ahmad (Author), Mohammed S. Alqahtani (Author), Arshad Mahmood (Author), Kashif Barkat (Author), Muhammad Tariq Khan (Author), Ume Ruqia Tulain (Author), Ayesha Rashid (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this work, series of pH-responsive hydrogels (FMA1-FMA9) were synthesized, characterized, and evaluated as potential carrier for oral delivery of an antiviral drug, acyclovir (ACV). Different proportions of β-cyclodextrin (β-CD), chitosan (CS), methacrylic acid (MAA) and N' N'-methylene...