Suppression of Coronary Atherosclerosis by Helix B Surface Peptide, a Nonerythropoietic, Tissue-Protective Compound Derived from Erythropoietin

• Main Authors: Hiroto Ueba (Author), Masashi Shiomi (Author), Michael Brines (Author), Michael Yamin (Author), Tsutomu Kobayashi (Author), Junya Ako (Author), Shin-ichi Momomura (Author), Anthony Cerami (Author), Masanobu Kawakami (Author)
• Format: Book
• Published: BMC, 2013-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Erythropoietin (EPO), a type I cytokine originally identified for its critical role in hematopoiesis, has been shown to have non-hematopoietic, tissue-protective effects, including suppression of atherosclerosis. However, prothrombotic effects of EPO hinder its potential clinical use in non...