Amphipathic barbiturates as marine product mimics with cytolytic and immunogenic effects on head and neck squamous cell carcinoma cell lines

• Main Authors: Susannah von Hofsten (Author), Manuel K. Langer (Author), Katja Korelin (Author), Synnøve Magnussen (Author), Dominik Ausbacher (Author), Trude Anderssen (Author), Tuula Salo (Author), Morten B. Strøm (Author), Annette Bayer (Author), Ahmed Al-Samadi (Author), Gerd Berge (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The incidence of head and neck squamous cell carcinoma (HNSCC) is increasing and the conventional treatments for this form of cancer can be tough. Despite the success of existing immunotherapies in some HNSCC patients, many do not respond to this type of treatment. Thus, the development of novel ant...