How drug repurposing can advance drug discovery: challenges and opportunities

• Váldodahkkit: Luca Pinzi (Dahkki), Nicolò Bisi (Dahkki), Giulio Rastelli (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Traditional de novo drug discovery, which typically presents an 11% approval rate from phase I trials and even higher failure rates in fields like neurodegeneration, often requires two to three billion dollars and 10-17 years per new drug. In contrast, drug repurposing can reduce risks and bring dru...