Lifespan analysis of brain development, gene expression and behavioral phenotypes in the Ts1Cje, Ts65Dn and Dp(16)1/Yey mouse models of Down syndrome
Down syndrome (DS) results from triplication of human chromosome 21. Neuropathological hallmarks of DS include atypical central nervous system development that manifests prenatally and extends throughout life. As a result, individuals with DS exhibit cognitive and motor deficits, and have delays in...
Saved in:
Main Authors: | Nadine M. Aziz (Author), Faycal Guedj (Author), Jeroen L. A. Pennings (Author), Jose Luis Olmos-Serrano (Author), Ashley Siegel (Author), Tarik F. Haydar (Author), Diana W. Bianchi (Author) |
---|---|
Format: | Book |
Published: |
The Company of Biologists,
2018-06-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Longitudinal neuroanatomical and behavioral analyses show phenotypic drift and variability in the Ts65Dn mouse model of Down syndrome
by: Patricia R. Shaw, et al.
Published: (2020) -
Timing of Treatment with the Flavonoid 7,8-DHF Critically Impacts on Its Effects on Learning and Memory in the Ts65Dn Mouse
by: Andrea Giacomini, et al.
Published: (2019) -
Oxidative-Stress-Associated Proteostasis Disturbances and Increased DNA Damage in the Hippocampal Granule Cells of the Ts65Dn Model of Down Syndrome
by: Alba Puente-Bedia, et al.
Published: (2022) -
Impaired Brain Mitochondrial Bioenergetics in the Ts65Dn Mouse Model of Down Syndrome Is Restored by Neonatal Treatment with the Polyphenol 7,8-Dihydroxyflavone
by: Daniela Valenti, et al.
Published: (2021) -
Preface / Ts Jamal Othman
by: Othman, Jamal
Published: (2021)