Changes of electrocardiogram and hemodynamics in response to dipyridamole: In vivo comparative analyses using anesthetized beagle dogs and microminipigs

• Main Authors: Kentaro Ando (Author), Akira Takahara (Author), Yuji Nakamura (Author), Takeshi Wada (Author), Koki Chiba (Author), Ai Goto (Author), Nur Jaharat Lubna (Author), Mihoko Hagiwara-Nagasawa (Author), Hiroko Izumi-Nakaseko (Author), Kiyotaka Hoshiai (Author), Yasuki Akie (Author), Atsuhiko T. Naito (Author), Atsushi Sugiyama (Author)
• Format: Book
• Published: Elsevier, 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Microminipigs are expected as a novel animal model for cardiovascular pharmacological experiments. Since inherent vulnerability of coronary circulation of microminipigs has not been characterized, we performed dipyridamole-stress test to both microminipigs and beagle dogs, and compared the results....