Insulin-sensitizing effects of vitamin D repletion mediated by adipocyte vitamin D receptor: Studies in humans and mice

• Main Authors: Eric Lontchi-Yimagou (Author), Sona Kang (Author), Akankasha Goyal (Author), Kehao Zhang (Author), Jee Y. You (Author), Michelle Carey (Author), Swati Jain (Author), Shobhit Bhansali (Author), Sylvia Kehlenbrink (Author), Peng Guo (Author), Evan D. Rosen (Author), Preeti Kishore (Author), Meredith Hawkins (Author)
• Format: Book
• Published: Elsevier, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Adipose tissue inflammation and fibrosis appear to contribute to insulin resistance in obesity. Vitamin D receptor (Vdr) genes are expressed by adipocytes, macrophages, and fibroblasts, all of which could potentially play a role in adipose tissue inflammation and fibrosis. As vitamin D ha...