Effects of moxifloxacin on the proarrhythmic surrogate markers in healthy Filipino subjects: Exposure-response modeling using ECG data of thorough QT/QTc study
Effects of moxifloxacin on QTc as well as proarrhythmic surrogate markers including J-Tpeakc, Tpeak-Tend and short-term variability (STV) of repolarization were examined by using both standard E14 time-based evaluation and exposure-response modeling. The study was conducted with a single-blind, rand...
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Main Authors: | Suchitra Matsukura (Author), Yuji Nakamura (Author), Kiyotaka Hoshiai (Author), Takashi Hayashi (Author), Tadashi Koga (Author), Ai Goto (Author), Koki Chiba (Author), Nur Jaharat Lubna (Author), Mihoko Hagiwara-Nagasawa (Author), Hiroko Izumi-Nakaseko (Author), Kentaro Ando (Author), Atsuhiko T. Naito (Author), Atsushi Sugiyama (Author) |
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Format: | Book |
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Elsevier,
2018-04-01T00:00:00Z.
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