Altered gut microbiota-host bile acid metabolism in IBS-D patients with liver depression and spleen deficiency pattern

• Main Authors: Liqing Du (Author), Zhaozhou Zhang (Author), Lixiang Zhai (Author), Shujun Xu (Author), Wei Yang (Author), Chunhua Huang (Author), Chengyuan Lin (Author), Linda L. D. Zhong (Author), Zhaoxiang Bian (Author), Ling Zhao (Author)
• Format: Book
• Published: BMC, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Dysregulation of gut microbiota-host bile acid (BA) co-metabolism is a critical pathogenic factor of diarrhea-predominant irritable bowel syndrome (IBS-D). Traditional Chinese Medicine (TCM), instructed by pattern differentiation, is effective in treating IBS-D, in which liver de...