Mesenchymal Stem Cells Promote the Osteogenesis in Collagen-Induced Arthritic Mice through the Inhibition of TNF-α

• Main Authors: Chang Liu (Author), Huayong Zhang (Author), Xiaojun Tang (Author), Ruihai Feng (Author), Genhong Yao (Author), Weiwei Chen (Author), Wenchao Li (Author), Jun Liang (Author), Xuebing Feng (Author), Lingyun Sun (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective. To investigate the effects of umbilical cord mesenchymal stem cell (UC-MSC) transplantation on joint damage and osteoporosis in collagen-induced arthritis (CIA) mice and to explore the mechanisms by which UC-MSCs modulate the osteogenic differentiation. Methods. CIA mice were divided into...