Tissue alkaline phosphatase activity and expression in an experimental infant swine model of cardiopulmonary bypass with deep hypothermic circulatory arrest

• Main Authors: Ludmila Khailova (Author), Justin Robison (Author), James Jaggers (Author), Richard Ing (Author), Scott Lawson (Author), Amy Treece (Author), Danielle Soranno (Author), Suzanne Osorio Lujan (Author), Jesse A. Davidson (Author)
• Format: Book
• Published: BMC, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Infant cardiac surgery with cardiopulmonary bypass results in decreased circulating alkaline phosphatase that is associated with poor postoperative outcomes. Bovine intestinal alkaline phosphatase infusion represents a novel therapy for post-cardiac surgery organ injury. However,...