A Copy Number Variant on Chromosome 20q13.3 Implicated in Thinness and Severe Obesity

• Hauptverfasser: Sandra J. Hasstedt (Verfasst von), Yuanpei Xin (Verfasst von), Rong Mao (Verfasst von), Tracey Lewis (Verfasst von), Ted D. Adams (Verfasst von), Steven C. Hunt (Verfasst von)
• Format: Buch
• Veröffentlicht: Hindawi Limited, 2015-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Background/Objectives. To identify copy number variants (CNVs) which are associated with body mass index (BMI). Subjects/Methods. CNVs were identified using array comparative genomic hybridization (aCGH) on members of pedigrees ascertained through severely obese (BMI ≥ 35 kg/m2) sib pairs (86 pedigr...