Na+/Ca2+ Exchanger 1/2 Double-Heterozygote Knockout Mice Display Increased Nitric Oxide Component and Altered Colonic Motility

• Main Authors: Kazuhiro Nishiyama (Author), Yasu-Taka Azuma (Author), Satomi Kita (Author), Naoki Azuma (Author), Satomi Hayashi (Author), Hidemitsu Nakajima (Author), Takahiro Iwamoto (Author), Tadayoshi Takeuchi (Author)
• Format: Book
• Published: Elsevier, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The Na+/Ca2+ exchanger (NCX) is a plasma membrane transporter involved in regulating intracellular Ca2+ concentrations. NCX is critical for Ca2+ regulation in cardiac muscle, vascular smooth muscle, and nerve fibers. To determine the role of NCX1 and NCX2 in gastrointestinal tissues, we examined ele...