Identification of Cell-Surface Proteins Endocytosed by Human Brain Microvascular Endothelial Cells In Vitro

• Main Authors: Shingo Ito (Author), Mariko Oishi (Author), Seiryo Ogata (Author), Tatsuki Uemura (Author), Pierre-Olivier Couraud (Author), Takeshi Masuda (Author), Sumio Ohtsuki (Author)
• Format: Book
• Published: MDPI AG, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cell-surface proteins that can endocytose into brain microvascular endothelial cells serve as promising candidates for receptor-mediated transcytosis across the blood-brain barrier (BBB). Here, we comprehensively screened endocytic cell-surface proteins in hCMEC/D3 cells, a model of human brain micr...