Activation of STING Pathway Contributed to Cisplatin-Induced Cardiac Dysfunction via Promoting the Activation of TNF-α-AP-1 Signal Pathway

• Κύριοι συγγραφείς: Lintao Wang (Συγγραφέας), Suya Zhang (Συγγραφέας), Jibo Han (Συγγραφέας), Xiaoyan Nie (Συγγραφέας), Yajun Qi (Συγγραφέας), Yingying Han (Συγγραφέας), Xiong Chen (Συγγραφέας), Chaoyong He (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Cardiovascular complications are a well-documented limitation of conventional cancer chemotherapy. As a notable side effect of cisplatin, cardiotoxicity represents a major obstacle to the treatment of cancer. Recently, it has been reported that cyclic GMP-AMP synthase (cGAS) stimulator of interferon...