Proteomic analysis of plasma exosomes from Cystic Echinococcosis patients provides in vivo support for distinct immune response profiles in active vs inactive infection and suggests potential biomarkers.

• Main Authors: Federica Fratini (Author), F Tamarozzi (Author), G Macchia (Author), L Bertuccini (Author), M Mariconti (Author), C Birago (Author), A Iriarte (Author), E Brunetti (Author), C M Cretu (Author), O Akhan (Author), M Siles-Lucas (Author), A Díaz (Author), Adriano Casulli (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The reference diagnostic method of human abdominal Cystic Echinococcosis (CE) is imaging, particularly ultrasound, supported by serology when imaging is inconclusive. However, current diagnostic tools are neither optimal nor widely available. The availability of a test detecting circulating biomarke...