Assessment of the In Vitro Phosphatidylinositol Glycan Class A (PIG-A) Gene Mutation Assay Using Human TK6 and Mouse Hepa1c1c7 Cell Lines

Gene mutations linked to diseases like cancer may be caused by exposure to environmental chemicals. The X-linked phosphatidylinositol glycan class A (PIG-A) gene, required for glycosylphosphatidylinositol (GPI) anchor biosynthesis, is a key target locus for in vitro genetic toxicity assays. Various...

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Main Authors: Wenhao Zhang (Author), Charles A. Miller (Author), Mark J. Wilson (Author)
Format: Book
Published: MDPI AG, 2024-09-01T00:00:00Z.
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