Two-step regulation by matrix Gla protein in brown adipose cell differentiation

• Main Authors: Li Zhang (Author), Xinjiang Cai (Author), Feiyang Ma (Author), Xiaojing Qiao (Author), Jaden Ji (Author), Jocelyn A. Ma (Author), Laurent Vergnes (Author), Yan Zhao (Author), Yucheng Yao (Author), Xiuju Wu (Author), Kristina I. Boström (Author)
• Format: Book
• Published: Elsevier, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Bone morphogenetic protein (BMP) signaling is intricately involved in adipose tissue development. BMP7 together with BMP4 have been implicated in brown adipocyte differentiation but their roles during development remains poorly specified. Matrix Gla protein (MGP) inhibits BMP4 and BMP7 an...