Ailanthone ameliorates pulmonary fibrosis by suppressing JUN-dependent MEOX1 activation

• Main Authors: Lixin Zhao (Author), Yuguang Zhu (Author), Hua Tao (Author), Xiying Chen (Author), Feng Yin (Author), Yingyi Zhang (Author), Jianfeng Qin (Author), Yongyin Huang (Author), Bikun Cai (Author), Yonghao Lin (Author), Jiaxiang Wu (Author), Yu Zhang (Author), Lu Liang (Author), Ao Shen (Author), Xi-Yong Yu (Author)
• Format: Book
• Published: Elsevier, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pulmonary fibrosis poses a significant health threat with very limited therapeutic options available. In this study, we reported the enhanced expression of mesenchymal homobox 1 (MEOX1) in pulmonary fibrosis patients, especially in their fibroblasts and endothelial cells, and confirmed MEOX1 as a ce...