Formulation and Evaluation of Gastro-retentive Drug Delivery Systems of Cinnarizine

• Main Authors: Hiyanki Patel (Author), CSR Lakshmi (Author), Krithi Nanaiah (Author), Chaya H N (Author)
• Format: Book
• Published: Rajiv Gandhi University of Health Sciences, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and Aim Cinnarizine is an antihistamine and calcium channel blocker used for the treatment of vertigo and vomiting. It has poor bioavailability and a half-life of 3.4 hours. Cinnarizine has low solubility and low dissolution rate in the gastrointestinal tract which causes the main problem...