Mechanisms of chemotherapy‐induced muscle wasting in mice with cancer cachexia

• Main Authors: Kate T. Murphy (Author), Kristy Swiderski (Author), James G. Ryall (Author), Jonathan R. Davey (Author), Hongwei Qian (Author), Séverine Lamon (Author), Victoria C. Foletta (Author), Jennifer Trieu (Author), Annabel Chee (Author), Suzannah J. Read (Author), Timur Naim (Author), Paul Gregorevic (Author), Gordon S. Lynch (Author)
• Format: Book
• Published: Wiley, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cachexia is a debilitating complication of cancer characterized by progressive wasting and weakness of skeletal muscles that reduces quality of life and can compromise survival. Many anticancer treatments, such as chemotherapy, also cause muscle wasting, which impairs the respons...