Intravitreal aflibercept protects photoreceptors of mice against excessive light exposure

• Main Authors: Yoshiki Kuse (Author), Kei Takahashi (Author), Yuki Inoue (Author), Hiroshi Izawa (Author), Shinsuke Nakamura (Author), Masamitsu Shimazawa (Author), Hideaki Hara (Author)
• Format: Book
• Published: Elsevier, 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Our previous studies found that an anti-placental growth factor (PlGF) antibody protected the retina in light-induced retinal damage model, a model of non-exudative age-related macular degeneration (AMD). Aflibercept is an inhibitor of vascular endothelial growth factor (VEGF) and PlGF. In present s...