18F-FDG PET/CT metrics-based stratification of large B-cell lymphoma receiving CAR-T cell therapy: immunosuppressive tumor microenvironment as a negative prognostic indicator in patients with high tumor burden

• Main Authors: Ling-Shuang Sheng (Author), Rong Shen (Author), Zi-Xun Yan (Author), Chao Wang (Author), Xin Zheng (Author), Yi-Lun Zhang (Author), Hao-Xu Yang (Author), Wen Wu (Author), Peng-Peng Xu (Author), Shu Cheng (Author), Emmanuel Bachy (Author), Pierre Sesques (Author), Nicolas Jacquet-Francillon (Author), Xu-Feng Jiang (Author), Wei-Li Zhao (Author), Li Wang (Author)
• Format: Book
• Published: BMC, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Chimeric antigen receptor T (CAR-T) cell therapy has greatly improved the prognosis of relapsed and refractory patients with large B-cell lymphoma (LBCL). Early identification and intervention of patients who may respond poorly to CAR-T cell therapy will help to improve the efficacy. Ninety...