Mapping the transcriptional landscape of human white and brown adipogenesis using single-nuclei RNA-seq

• Main Authors: Anushka Gupta (Author), Vissarion Efthymiou (Author), Sean D. Kodani (Author), Farnaz Shamsi (Author), Mary Elizabeth Patti (Author), Yu-Hua Tseng (Author), Aaron Streets (Author)
• Format: Book
• Published: Elsevier, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Adipogenesis is key to maintaining organism-wide energy balance and healthy metabolic phenotype, making it critical to thoroughly comprehend its molecular regulation in humans. By single-nuclei RNA-sequencing (snRNA-seq) of over 20,000 differentiating white and brown preadipocytes, we constructed a...