Relationship between CYP3A5 Polymorphism and Tacrolimus Blood Concentration Changes in Allogeneic Hematopoietic Stem Cell Transplant Recipients during Continuous Infusion
A polymorphism in the gene encoding the metabolic enzyme cytochrome P450 family 3 subfamily A member 5 (CYP3A5) is a particularly influential factor in the use of tacrolimus in Japanese patients. Those who are homozygotic for the <i>*3</i> mutation lack CYP3A5 activity, which results in...
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| Main Authors: | , , , , , , |
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| Format: | Book |
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MDPI AG,
2021-04-01T00:00:00Z.
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