Noma affected children from Niger have distinct oral microbial communities based on high-throughput sequencing of 16S rRNA gene fragments.

• Main Authors: Katrine L Whiteson (Author), Vladimir Lazarevic (Author), Manuela Tangomo-Bento (Author), Myriam Girard (Author), Heather Maughan (Author), Didier Pittet (Author), Patrice Francois (Author), Jacques Schrenzel (Author), GESNOMA study group (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We aim to understand the microbial ecology of noma (cancrum oris), a devastating ancient illness which causes severe facial disfigurement in>140,000 malnourished children every year. The cause of noma is still elusive. A chaotic mix of microbial infection, oral hygiene and weakened immune system...