Peri-tumor administration of 5-fluorouracil sol-gel using a hollow microneedle for treatment of gastric cancer

• Main Authors: Yoon Suk Jung (Author), Dong-Hoe Koo (Author), Jeong-Yoon Yang (Author), Hee-Young Lee (Author), Jung-Hwan Park (Author), Jung Ho Park (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of this study was to investigate the effectiveness of treating gastric cancer by injecting a pluronic F-127 sol-gel formulation of 5-fluorouracil (5-FU) into normal tissue surrounding the tumor using a hollow microneedle. The MTS tetrazolium assay was performed to assess the cytotoxicity of...