Establishment of drug-resistant HBV small-animal models by hydrodynamic injection

In antiviral therapy of hepatitis B virus (HBV) infection, drug resistance remains a huge obstacle to the long-term effectiveness of nucleoside/tide analogs (NAs). Primary resistance mutation (rtM204V) contributes to lamivudine (LAM)-resistance, and compensatory mutations (rtL180M and rtV173L) resto...

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Main Authors: Junjun Cheng (Author), Yanxing Han (Author), Jian-Dong Jiang (Author)
Format: Book
Published: Elsevier, 2014-08-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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