Establishment of drug-resistant HBV small-animal models by hydrodynamic injection
In antiviral therapy of hepatitis B virus (HBV) infection, drug resistance remains a huge obstacle to the long-term effectiveness of nucleoside/tide analogs (NAs). Primary resistance mutation (rtM204V) contributes to lamivudine (LAM)-resistance, and compensatory mutations (rtL180M and rtV173L) resto...
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| Main Authors: | , , |
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| Format: | Book |
| Published: |
Elsevier,
2014-08-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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