Comprehensive analysis of the secreted proteome of adult Necator americanus hookworms.

• Main Authors: Jayden Logan (Author), Mark S Pearson (Author), Srikanth S Manda (Author), Young-Jun Choi (Author), Matthew Field (Author), Ramon M Eichenberger (Author), Jason Mulvenna (Author), Shivashankar H Nagaraj (Author), Ricardo T Fujiwara (Author), Pedro Gazzinelli-Guimaraes (Author), Lilian Bueno (Author), Vitor Mati (Author), Jeffrey M Bethony (Author), Makedonka Mitreva (Author), Javier Sotillo (Author), Alex Loukas (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The human hookworm Necator americanus infects more than 400 million people worldwide, contributing substantially to the poverty in these regions. Adult stage N. americanus live in the small intestine of the human host where they inject excretory/secretory (ES) products into the mucosa. ES products h...