Carbonic anhydrase inhibitory activity of phthalimide-capped benzene sulphonamide derivatives

• Main Authors: Deepak Shilkar (Author), Mohd Usman Mohd Siddique (Author), Silvia Bua (Author), Sabina Yasmin (Author), Mrunali Patil (Author), Ajay Kumar Timiri (Author), Claudiu T. Supuran (Author), Venkatesan Jayaprakash (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A series of phthalimide-capped benzene sulphonamides (1-22) reported by our group for dengue protease inhibitory activity have been evaluated for their carbonic anhydrase (hCA, EC 4.2.1.1) inhibitory activity against hCA I, hCA II. Compounds 1, 3, 10, and 15 showed hCA I inhibition, whereas 1, 4, an...