Improved GMP-compliant multi-dose production and quality control of 6-[18F]fluoro-L-DOPA

• Main Authors: G. Luurtsema (Author), H. H. Boersma (Author), M. Schepers (Author), A. M. T. de Vries (Author), B. Maas (Author), R. Zijlma (Author), E. F. J. de Vries (Author), P. H. Elsinga (Author)
• Format: Book
• Published: SpringerOpen, 2016-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background 6-[18F]Fluoro-L-3,4-dihydroxyphenylalanine (FDOPA) is a frequently used radiopharmaceutical for detecting neuroendocrine and brain tumors and for the differential diagnosis of Parkinson's disease. To meet the demand for FDOPA, a high-yield GMP-compliant production method is...