Genetic variants in the TIRAP gene are associated with increased risk of sepsis-associated acute lung injury

• Main Authors: Jiang Jinjun (Author), Yao Chenling (Author), Shen Yao (Author), Sun Zhan (Author), Tong Chaoyang (Author), Song Zhenju (Author), Yin Jun (Author), Gao Lei (Author), Song Yuanlin (Author), Bai Chunxue (Author)
• Format: Book
• Published: BMC, 2010-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Toll like receptors (TLRs) signaling pathways, including the adaptor protein Mal encoded by the TIRAP gene, play a central role in the development of acute lung injury (ALI). Recently, the <it>TIRAP </it>variants have bee...