Blocking the IGF2BP1-promoted glucose metabolism of colon cancer cells via direct de-stabilizing mRNA of the LDHA enhances anticancer effects

Colorectal cancer (CRC) is a commonly diagnosed cancer with poor prognosis and high mortality rate. Hyperthermia (HT) is an adjunctive therapy to enhance the antitumor effects of traditional chemo- or radio- therapy. Here, we report that a cluster of essential regulator genes and speed-limit enzymes...

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Main Authors: Xiang-liang Zhang (Author), Ke-jun Li (Author), Jin-xin Feng (Author), Gao-jie Liu (Author), Yan-lin Feng (Author)
Format: Book
Published: Elsevier, 2021-03-01T00:00:00Z.
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