Blocking the IGF2BP1-promoted glucose metabolism of colon cancer cells via direct de-stabilizing mRNA of the LDHA enhances anticancer effects
Colorectal cancer (CRC) is a commonly diagnosed cancer with poor prognosis and high mortality rate. Hyperthermia (HT) is an adjunctive therapy to enhance the antitumor effects of traditional chemo- or radio- therapy. Here, we report that a cluster of essential regulator genes and speed-limit enzymes...
Saved in:
Main Authors: | Xiang-liang Zhang (Author), Ke-jun Li (Author), Jin-xin Feng (Author), Gao-jie Liu (Author), Yan-lin Feng (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2021-03-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
IGF2BP3 promotes glutamine metabolism of endometriosis by interacting with UCA1 to enhances the mRNA stability of GLS1
by: Honglin Wang, et al.
Published: (2024) -
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) in hematological diseases
by: Shuangping Ma, et al.
Published: (2024) -
CircNRIP1 promotes proliferation, migration and phenotypic switch of Ang II-induced HA-VSMCs by increasing CXCL5 mRNA stability via recruiting IGF2BP1
by: Xianzhao Cao, et al.
Published: (2024) -
Therapeutic potential for mRNA-based IGF-I regenerative therapy
by: Cynthia D. Anderson
Published: (2024) -
Indole-3-Carbinol Stabilizes p53 to Induce miR-34a, Which Targets LDHA to Block Aerobic Glycolysis in Liver Cancer Cells
by: Yuehua Qi, et al.
Published: (2022)