Intramolecular activity regulation of adhesion GPCRs in light of recent structural and evolutionary information

• Main Authors: Gunnar Kleinau (Author), Amal Hassan Ali (Author), Franziska Wiechert (Author), Michal Szczepek (Author), Andrea Schmidt (Author), Christian M.T. Spahn (Author), Ines Liebscher (Author), Torsten Schöneberg (Author), Patrick Scheerer (Author)
• Format: Book
• Published: Elsevier, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The class B2 of GPCRs known as adhesion G protein-coupled receptors (aGPCRs) has come under increasing academic and nonacademic research focus over the past decade due to their physiological importance as mechano-sensors in cell-cell and cell-matrix contexts. A major advance in understanding signal...