Intramolecular activity regulation of adhesion GPCRs in light of recent structural and evolutionary information

• Egile Nagusiak: Gunnar Kleinau (Egilea), Amal Hassan Ali (Egilea), Franziska Wiechert (Egilea), Michal Szczepek (Egilea), Andrea Schmidt (Egilea), Christian M.T. Spahn (Egilea), Ines Liebscher (Egilea), Torsten Schöneberg (Egilea), Patrick Scheerer (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2023-11-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The class B2 of GPCRs known as adhesion G protein-coupled receptors (aGPCRs) has come under increasing academic and nonacademic research focus over the past decade due to their physiological importance as mechano-sensors in cell-cell and cell-matrix contexts. A major advance in understanding signal...