Contribution of Connexin Hemichannels to the Pathogenesis of Acute Lung Injury

• Main Authors: Shuaiwei Wang (Author), Yafang Sun (Author), Yu Bai (Author), Nannan Zhou (Author), Na Chen (Author), Edmund J. Miller (Author), Yijie Zhang (Author), Wei Li (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Connexin (Cx) family members form hemichannels (HCs) and gap junctions (GJs). Biological functions of Cx HCs have not been adequately characterized due to the inability to selectively target HCs or GJs. Recently, we developed a 6-mer peptide mimetic (P5) of the first extracellular loop of Cx43 and s...