Protein and metabolic profiles of tyrosine kinase inhibitors co-resistant liver cancer cells

• Main Authors: Zengbin Wang (Author), Linqing Wu (Author), Yu Zhou (Author), Zhong Chen (Author), Tao Zhang (Author), Hong Wei (Author), Zhihong Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hepatocellular Carcinoma (HCC) patients often develop resistance to tyrosine kinase inhibitors (TKIs) like sorafenib (SR) and lenvatinib (RR). We established HCC cell lines resistant to these drugs and analyzed the correlation between protein and metabolite profiles using bioinformatics. Our analysi...