Pretreatment with platelet-rich plasma protects against ischemia-reperfusion induced flap injury by deactivating the JAK/STAT pathway in mice

• Egile Nagusiak: Linlin Su (Egilea), Songtao Xie (Egilea), Ting Li (Egilea), Yanhui Jia (Egilea), Yunchuan Wang (Egilea)
• Formatua: Liburua
• Argitaratua: BMC, 2024-02-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Background Ischemia-reperfusion (I/R) injury is a major cause of surgical skin flap compromise and organ dysfunction. Platelet-rich plasma (PRP) is an autologous product rich in growth factors, with tissue regenerative potential. PRP has shown promise in multiple I/R-induced tissue injuries...